Lipaglyn Tablet 10’s is an insulin sensitiser used to treat diabetic dyslipidaemia/hypertriglyceridemia in type-2 diabetic patients, which is not controlled by statins (lipid-lowering agents) alone. Lipaglyn Tablet 10’s has both lipid and glucose-lowering effects in a single molecule; thereby, helps lower blood triglycerides and blood glucose levels. Diabetic dyslipidaemia is characterised by increased triglyceride levels, low-density lipoproteins (LDL) and decreased high-density lipoprotein (HDL) levels. This condition is common in people with type-2 diabetes mellitus.
Lipaglyn Tablet 10’s contains ‘Saroglitazar’, which has dual Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ agonist having strong PPAR-alpha effect and moderate PPAR-gamma effect. PPAR-alpha reduces the synthesis and secretion of triglycerides, increases lipolysis and hepatic oxidation of fatty acids. It also induces an increase in the synthesis of HDL cholesterol. PPAR-gamma reduces the metabolic burden on the liver, muscle and promotes glucose utilisation. It improves post-absorptive insulin-mediated suppression of hepatic glucose output. Thereby, Lipaglyn Tablet 10’s helps in lowering blood triglycerides and blood glucose levels.
You are advised to take Lipaglyn Tablet 10’s for as long as your doctor has prescribed it, depending on your medical condition. In some cases, you may experience certain common side effects such as stomach inflammation, nausea, vomiting, weakness, chest discomfort, dizziness, and fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if you experience these side effects persistently.
Consult your doctor if you are pregnant. It is not known if Lipaglyn Tablet 10’s is excreted into breastmilk; therefore, nursing mothers should avoid taking Lipaglyn Tablet 10’s. Lipaglyn Tablet 10’s should not be given to children as safety and effectiveness have not been established. Lipaglyn Tablet 10’s should be used with caution in patients with kidney or liver impairment and in elderly patients. Avoid alcohol consumption while taking Lipaglyn Tablet 10’s as it might cause unpleasant side-effects. Lipaglyn Tablet 10’s might cause dizziness, so drive with caution. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects.
Medicinal Benefits
Lipaglyn Tablet 10’s is an insulin sensitiser used to treat diabetic dyslipidaemia/hypertriglyceridemia in type-2 diabetes, which is not controlled by statins alone. Lipaglyn Tablet 10’s has demonstrated reduction of triglycerides (TG), Low-Density Lipoprotein (LDL) cholesterol, non-High-Density Lipoprotein (non- HDL) cholesterol, Very Low-Density Lipoprotein (VLDL) cholesterol, and an increase in HDL cholesterol. It has also shown glycemic indices by lowering the fasting plasma glucose and glycosylated haemoglobin in diabetic patients. Lipaglyn Tablet 10’s has dual Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ agonist having strong PPAR-alpha effect and moderate PPAR-gamma effect. PPAR-alpha reduces the synthesis and secretion of triglycerides, increases lipolysis and hepatic oxidation of fatty acids. It also induces an increase in the synthesis of HDL cholesterol. PPAR-gamma reduces the metabolic burden on the liver, muscle and promotes glucose utilisation, and improves post-absorptive insulin-mediated suppression of hepatic glucose output. Lipaglyn Tablet 10’s has both lipid and glucose-lowering effects in a single molecule; this helps in lowering blood triglycerides and blood glucose levels as well. It also helps in improving insulin resistance. Lipaglyn Tablet 10’s offers a superior safety profile, greater efficacy on lipid regulation, and excellent glycaemic control.
Drug Warnings
Do not take Lipaglyn Tablet 10’s if you are allergic to any of the components. Inform your doctor if you notice rapid weight gain. Consult your doctor before taking Lipaglyn Tablet 10’s if you are pregnant. It is not known if Lipaglyn Tablet 10’s is excreted into breastmilk; therefore, nursing mothers should avoid taking Lipaglyn Tablet 10’s. Lipaglyn Tablet 10’s should not be given to children as safety and effectiveness have not been established. Lipaglyn Tablet 10’s might cause dizziness, so drive with caution. Avoid alcohol consumption while taking Lipaglyn Tablet 10’s as it might cause unpleasant side-effects. Lipaglyn Tablet 10’s should be used with caution in patients with type-2 diabetes having cardiovascular disease.
HOW TO USE LIPAGLYN TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lipaglyn Tablet may be taken with or without food, but it is better to take it at a fixed time.
HOW LIPAGLYN TABLET WORKS
Lipaglyn Tablet contains Saroglitazar, a dual action peroxisome proliferator-activated receptor (PPAR) inhibitor that aids in the management of high cholesterol, especially triglycerides, as well as blood sugar levels in people with type 2 diabetes. It acts by a unique mechanism in which it reduces the synthesis and secretion of triglycerides (a type of lipid or cholesterol in blood). It also improves insulin sensitivity of the body for better utilization of the existing insulin and hence lowers the blood sugar levels.
Disclaimer
The product information contained herein is for informational purposes only, and is not intended to diagnose, treat, or prevent any disease or health condition. Pharmville Pharmacy does not endorse the appropriateness or reliability of this information and is not responsible if the content is not accurate, complete or current. Your use of this information is entirely at your own risk, and in no event shall Pharmville Pharmacy be liable for any loss or damage arising out of, or in connection with, the use of this material.
